1583-59-1 | 2,2-Difluoro-1,3-benzodioxole

CAS:1583-59-1 | 2,2-Difluoro-1,3-benzodioxole ,Description

2,2-Difluoro-1,3-benzodioxole (DFBD) is a versatile chemical compound with a wide range of applications in scientific research. It has been used as a reagent for organic synthesis, as an intermediate for the synthesis of pharmaceuticals and as a building block for various materials. DFBD has also been studied for its biochemical and physiological effects, as well as its potential for use in laboratory experiments. 
 

Scientific Research Applications

• Anticancer and Antibacterial Properties: A derivative, specifically a 2-phenyl 1,3-benzodioxole compound, has been identified for its promising anticancer, antibacterial, and DNA-binding properties, suggesting potential for further development in these domains (Gupta et al., 2016).
• Conducting Polymers: Poly(2,2-dimethyl-1,3-benzodioxole) is noted for its low oxidation potential and high electrical conductivity, making it a prospective material for applications like electrodes and batteries (Xu Jing-kun, 2008).
• Medicinal and Agrochemical Applications: Fluorinated orthoesters derived from 1,3-benzodioxoles offer high stability and modifiable physicochemical properties, making them suitable candidates for medicinal or agrochemical applications (Röckl et al., 2019) .
• Photoinitiation for Polymerization: Naphthodioxinone-1,3-benzodioxole serves as a caged one-component Type II photoinitiator for free radical polymerization, crucial for materials science and engineering (Kumbaraci et al., 2012).
• Synthesis Methods: Several studies have developed efficient methods for synthesizing various 1,3-benzodioxole derivatives, including 2,2-disubstituted versions, which are significant for various chemical applications (Li et al., 2008; Gorecka et al., 2004).
• Atropisomeric Ligands: Novel atropisomeric bisphosphines derived from 2,2-Difluoro-1,3-benzodioxole have been prepared, showing potential as ligands for enantioselective catalysts (Leroux et al., 2004).
• Imaging Agents: Carbon-11-labeled CK1 inhibitors, potentially derivable from 2,2-Difluoro-1,3-benzodioxole, show promise as PET radiotracers for imaging of Alzheimer's disease (Gao et al., 2018).

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